Description

n-Oxalyl-L-Alanine is a high-purity, non-proteinogenic amino acid derivative featuring an oxalyl protecting group on the α-amino function. This compound is a critical building block in peptide synthesis and medicinal chemistry research, offering precise control over molecular structure. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in the development of novel therapeutic agents and biochemical probes.

Application

• Peptide Synthesis Intermediate: Serves as a key protected amino acid derivative for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Medicinal Chemistry Research: Used as a building block in the design and synthesis of novel drug candidates, enzyme inhibitors, and receptor ligands.
• Biochemical Probe Development: Employed in the creation of labeled or modified amino acids for studying enzyme mechanisms, protein-protein interactions, and metabolic pathways.
• Pharmaceutical Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API (Active Pharmaceutical Ingredient) development.
• Organic Synthesis Reagent: Functions as a chiral synthon for the asymmetric synthesis of more complex organic molecules with specific stereochemistry.

Basic Information

Product Name	n-Oxalyl-L-Alanine
CAS No.	5302-46-5
Molecular Formula	C5H7NO5
Molecular Weight	161.11 g/mol
Synonyms	L-Alanine, N-oxalyl-; Oxalyl-L-alanine; (S)-2-(Oxalylamino)propanoic acid; N-Oxalylalanine; 2-[(Oxalyl)amino]propanoic acid; Alantine, N-oxalyl-; NSC 163063
EINECS	Contact for details

Quality Control

Our n-Oxalyl-L-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.