Description

20,22-Dihydrodigoxin is a cardiac glycoside derivative and a key intermediate in the synthesis and research of related therapeutic compounds. This high-purity chemical is essential for pharmaceutical development, particularly in the study of structure-activity relationships and metabolic pathways of cardiac drugs. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and manufacturers specializing in active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel cardiac glycosides and related therapeutic agents.
• Biochemical Research: Used as a reference standard and research tool in pharmacological studies to investigate cardiac drug mechanisms and metabolism.
• Analytical Standard: Serves as a high-purity standard for quality control (QC) and analytical method development in pharmaceutical manufacturing.
• Metabolite Studies: Employed in the study of digoxin and related glycoside metabolism for toxicological and pharmacokinetic research.
• Academic Research: Utilized in university and institutional labs for cardiovascular research and medicinal chemistry projects.

Basic Information

Product Name	20,22-Dihydrodigoxin
CAS No.	5297-10-9
Molecular Formula	C₄₁H₆₄O₁₄
Molecular Weight	780.94 g/mol
Synonyms	Dihydrodigoxin; 3β,12β,14-Trihydroxy-5β-card-20(22)-enolide; 20,22-Dihydrodigoxigenin tri-digitoxoside; Digoxigenin tri-digitoxoside, dihydro-; 20,22-Dihydro-12β-hydroxydigitoxin; 20,22-Dihydrodigitoxin; 20,22-Dihydrodigoxigenin tridigitoxoside
EINECS	226-124-8

Quality Control

Our 20,22-Dihydrodigoxin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a detailed Certificate of Analysis (COA). We adhere to relevant industry standards suitable for research and pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.