Description

Boc-Trp-Met-Asp-Phe-Nh2 is a protected pentapeptide sequence featuring tryptophan, methionine, aspartic acid, and phenylalanine residues, with the N-terminus protected by a tert-butyloxycarbonyl (Boc) group. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins for research and development. It is primarily utilized by pharmaceutical researchers, biotech companies, and academic institutions engaged in peptide-based drug discovery, biochemical studies, and the development of therapeutic agents.

Application

• Peptide Drug Discovery & Development: Serves as a key intermediate in the synthesis of novel therapeutic peptides targeting various diseases.
• Biochemical Research: Used as a standard or reagent in studies of peptide structure, function, and receptor-ligand interactions.
• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the sequential, automated synthesis of longer, more complex peptide chains.
• Pharmaceutical Intermediates: Employed in the production of active pharmaceutical ingredients (APIs) for peptide-based medications.
• Proteomics & Molecular Biology: Utilized in the design and creation of peptide probes, substrates, or inhibitors for enzymatic assays.

Basic Information

Product Name	Boc-Trp-Met-Asp-Phe-Nh2
CAS No.	5235-21-2
Molecular Formula	C₃₈H₅₀N₆O₈S
Molecular Weight	750.91 g/mol
Synonyms	Boc-Tryptophan-Methionine-Aspartic Acid-Phenylalanine amide; Boc-Trp-Met-Asp-Phe-amide; N-α-(tert-Butoxycarbonyl)-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide; Boc-L-Trp-L-Met-L-Asp-L-Phe-NH₂; Boc-Trp-Met-Asp-Phe-NH2; Boc-W-M-D-F-NH₂; (tert-Butoxycarbonyl)tryptophylmethionylaspartylphenylalaninamide
EINECS	Contact for details

Quality Control

Our Boc-Trp-Met-Asp-Phe-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring the material meets the high standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.