Description

H-Cys(Dpm)-Oh is a protected cysteine derivative, a crucial building block in peptide synthesis and pharmaceutical research. Its primary value lies in providing a thiol-protecting group (Dpm) that is stable under acidic conditions, enabling selective deprotection strategies during complex peptide assembly. This compound is essential for researchers and manufacturers in the fields of pharmaceutical development, bioconjugation, and advanced organic synthesis.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for incorporating protected cysteine residues into peptide chains.
• Pharmaceutical Intermediates: Used in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation Chemistry: Serves as a precursor for creating thiol-reactive linkers for antibody-drug conjugates (ADCs) or protein labeling.
• Chemical Biology Research: Employed in the study of protein folding, disulfide bond formation, and enzyme activity.
• Custom Peptide Services: A fundamental reagent for contract research organizations (CROs) and CDMOs offering bespoke peptide manufacturing.
• Protecting Group Strategy: Utilized in multi-step organic syntheses where selective protection of the cysteine thiol group is required.

Basic Information

Product Name	H-Cys(Dpm)-Oh
CAS No.	5191-80-0
Molecular Formula	C14H21NO3S
Molecular Weight	283.39 g/mol
Synonyms	S-(Diphenylmethyl)-L-cysteine; L-Cysteine, S-(diphenylmethyl)-; S-Diphenylmethylcysteine; H-Cys(Dpm)-OH; Cysteine(Dpm)-OH; N-[(2R)-2-Amino-3-[(diphenylmethyl)sulfanyl]propanoyl]oxy; (R)-2-Amino-3-((diphenylmethyl)thio)propanoic acid
EINECS	Contact for details

Quality Control

Our H-Cys(Dpm)-Oh is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and our quality protocols are designed to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-20° to -25° (c=1 in AcOH)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.