Description

2-Amino-3-Hydroxy-3-Methylbutyric Acid is a non-proteinogenic amino acid derivative of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial chiral building block and intermediate for the synthesis of more complex molecules, including potential active pharmaceutical ingredients (APIs) and specialty fine chemicals. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in advanced organic synthesis and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in metabolic studies, enzyme substrate research, and as a precursor for synthesizing amino acid analogs.
• Peptide Synthesis: Serves as a specialized, non-standard amino acid residue for constructing modified peptides with unique properties.
• Fine Chemical Production: An important intermediate in the multi-step synthesis of complex organic compounds for high-value applications.
• Nutritional Science Research: Investigated for its potential role and effects in metabolic pathways related to branched-chain amino acids.

Basic Information

Product Name	2-Amino-3-Hydroxy-3-Methylbutyric Acid
CAS No.	5174-30-1
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	3-Hydroxyvaline; 3-Hydroxy-3-methyl-DL-norvaline; 2-Amino-3-hydroxy-3-methylbutanoic acid; HMB Amino Acid; α-Amino-β-hydroxyisovaleric acid; 3-Methyl-3-hydroxy-2-aminobutanoic acid; DL-3-Hydroxy-3-methylnorvaline
EINECS	225-947-4

Quality Control

Our 2-Amino-3-Hydroxy-3-Methylbutyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.