Description

5-Bromo-4-(Thiophen-2-Yl)Pyrimidine is a high-value brominated heterocyclic building block, essential for constructing complex molecular architectures in advanced research and development. This compound is critical for medicinal chemistry programs, enabling the synthesis of novel small molecules with potential therapeutic activity. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical companies, and specialty chemical manufacturers engaged in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used as a core scaffold for developing new fungicides and herbicides with novel modes of action.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	5-Bromo-4-(Thiophen-2-Yl)Pyrimidine
CAS No.	5162-74-3
Molecular Formula	C8H5BrN2S
Molecular Weight	241.11 g/mol
Synonyms	5-Bromo-4-(2-thienyl)pyrimidine; 4-(Thiophen-2-yl)-5-bromopyrimidine; 5-Bromo-4-(thiophen-2-yl)pyrimidine; 5-Bromo-4-thiophen-2-yl-pyrimidine; 2-Thienyl-5-bromopyrimidine; 5-Bromo-4-(2-thienyl)pyrimidine; 5162-74-3; 4-(2-Thienyl)-5-bromopyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-(Thiophen-2-Yl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.