Description

Norleucine is a non-proteinogenic, aliphatic amino acid that serves as a crucial biochemical building block and analytical standard. Its structural similarity to methionine and leucine makes it an invaluable tool for metabolic pathway studies and protein research. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and nutritional science sectors seeking precise, reliable materials for their critical processes.

Application

• Pharmaceutical Research & Development: Used as a reference standard in amino acid analysis, a metabolic inhibitor in biochemical studies, and a precursor in peptide synthesis.
• Nutritional Science & Supplementation: Investigated for its role in metabolic studies and as a component in specialized amino acid formulations for research purposes.
• Biotechnology & Cell Culture: Employed in media formulation for mammalian cell culture and as a tool to study amino acid transport and incorporation mechanisms.
• Chemical Synthesis: Serves as a chiral building block for the synthesis of more complex organic molecules, pharmaceuticals, and fine chemicals.
• Academic & Industrial Research: A fundamental reagent for studying enzyme specificity, protein structure-function relationships, and amino acid metabolism.

Basic Information

Product Name	Norleucine
CAS No.	5157-09-5
Molecular Formula	C6H13NO2
Molecular Weight	131.17 g/mol
Synonyms	2-Aminohexanoic Acid; L-Norleucine; (S)-2-Aminohexanoic Acid; H-Nle-OH; Norleucine, L-; NSC 7601; Hexanoic acid, 2-amino-; L-2-Aminohexanoic acid; (S)-Norleucine; 2-Amino-n-caproic acid
EINECS	225-926-5

Quality Control

Our Norleucine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting or exceeding specifications for research and industrial use. A detailed Certificate of Analysis (COA) is supplied with each batch, documenting key parameters such as assay, optical rotation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]	+20.0° to +24.0° (c=1 in 1N HCl)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.