Description

Cyclo(Tyr-Phe) CAS NO 5147-17-1 is a high-purity cyclic dipeptide, also known as a diketopiperazine (DKP), formed from the amino acids tyrosine and phenylalanine. This compound is valued for its structural rigidity and potential as a key intermediate or scaffold in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications in drug discovery, peptide chemistry, and biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of more complex peptide-based drugs and bioactive molecules.
• Drug Discovery Scaffold: Used in medicinal chemistry as a constrained scaffold to explore structure-activity relationships (SAR) and develop novel therapeutic agents.
• Biochemical Research: Employed in academic and industrial laboratories to study enzyme inhibition, receptor binding, and other biological interactions.
• Peptide Mimetic Development: Acts as a stable core structure for creating peptidomimetics with enhanced metabolic stability and bioavailability.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development and quality control of related compounds.

Basic Information

Product Name	Cyclo(Tyr-Phe)
CAS No.	5147-17-1
Molecular Formula	C18H18N2O3
Molecular Weight	310.35 g/mol
Synonyms	Cyclo(L-tyrosyl-L-phenylalanyl); Cyclo(Tyr-Phe) DKP; 3,6-Bis(benzyl)-2,5-piperazinedione (3S,6S)-isomer; L-Tyrosyl-L-phenylalanine anhydride; 2,5-Piperazinedione, 3-(4-hydroxybenzyl)-6-benzyl-, (3S,6S)-; Cyclo(L-Tyr-L-Phe); Cyclo(YP); DKPs
EINECS	225-889-2

Quality Control

Our Cyclo(Tyr-Phe) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.