Description

Cyclo(Phe-Gly) CAS NO 5037-75-2 is a cyclic dipeptide, also known as a diketopiperazine (DKP), formed from phenylalanine and glycine. This compound serves as a crucial pharmacological reference standard and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, drug discovery, and the development of novel bioactive molecules.

Application

• Pharmaceutical Reference Standard: Used for method development, calibration, and quality control in analytical laboratories for peptide-based drug analysis.
• Medicinal Chemistry Intermediate: Acts as a constrained scaffold or a core structure for synthesizing libraries of compounds in drug discovery programs.
• Biochemical Research: Employed in studies of peptide conformation, stability, and enzyme-substrate interactions due to its cyclic structure.
• Peptidomimetics Development: Serves as a key precursor for creating peptidomimetics, which are molecules that mimic the structure and function of natural peptides.
• Academic & Industrial R&D: Fundamental building block in organic synthesis for exploring new chemical reactions and creating complex molecular architectures.

Basic Information

Product Name	Cyclo(Phe-Gly)
CAS No.	5037-75-2
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	Cyclo(L-phenylalanylglycine); 3-Benzyl-2,5-piperazinedione; 3-Benzylpiperazine-2,5-dione; Cyclo(L-Phe-Gly); L-Phenylalanylglycine anhydride; DKPs; Diketopiperazine; Phenylalanine-Glycine Diketopiperazine
EINECS	225-714-9

Quality Control

Our Cyclo(Phe-Gly) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.