Description

5-Aminopyrimidine is a versatile heterocyclic aromatic amine that serves as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key precursor for the development of pharmaceuticals, agrochemicals, and specialty fine chemicals. This compound is particularly essential for researchers and manufacturers in the pharmaceutical industry, where it is used to synthesize active pharmaceutical ingredients (APIs), nucleoside analogs, and various biologically active molecules.

Application

• Pharmaceutical Intermediate: A fundamental synthon for the production of antiviral, anticancer, and antimicrobial drugs, including nucleoside reverse transcriptase inhibitors.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators that require a pyrimidine core structure.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in coordination chemistry and homogeneous catalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs).
• Biochemical Research: Utilized as a scaffold in medicinal chemistry for drug discovery and the development of enzyme inhibitors.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of certain specialized dyes and colorants.

Basic Information

Product Name	5-Aminopyrimidine
CAS No.	591-55-9
Molecular Formula	C4H5N3
Molecular Weight	95.10 g/mol
Synonyms	5-Pyrimidinamine; Pyrimidin-5-ylamine; 5-Amino-1,3-diazine; 1,3-Diazin-5-amine; 5-Pyrimidinylamine; 5-Amino-pyrimidine; Aminopyrimidine
EINECS	209-719-5

Quality Control

Our 5-Aminopyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material is suitable for demanding research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.