Description

α-Msh CAS NO 581-05-5 is a synthetic peptide analog of the endogenous α-melanocyte-stimulating hormone. This compound is a critical research and development tool for studying melanogenesis, appetite regulation, and anti-inflammatory pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on metabolic disorders, dermatology, and neuroendocrinology.

Application

• Pharmaceutical Research & Development: As a reference standard and active ingredient in preclinical studies for metabolic and dermatological conditions.
• Biochemical Assay Development: Used in the development and validation of in vitro bioassays targeting the melanocortin receptors (MC1R, MC3R, MC4R).
• Academic & Clinical Research: Investigating its role in skin pigmentation, energy homeostasis, and inflammatory response modulation.
• Peptide Chemistry Studies: Serving as a model compound for studying peptide stability, formulation, and delivery mechanisms.
• Cosmeceutical Research: Exploration of its potential in skin tanning and photoprotection applications.

Basic Information

Product Name	α-Msh
CAS No.	581-05-5
Molecular Formula	C77H109N21O19S
Molecular Weight	1664.9 g/mol
Synonyms	α-MSH; α-Melanocyte Stimulating Hormone; α-Melanotropin; Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2; Melanotropin alpha; Intermedin; Afamelanotide (related analog); [Nle4, D-Phe7]-α-MSH (common analog)
EINECS	Contact for details

Quality Control

Our α-Msh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation, mass spectrometry for molecular weight verification, and stringent tests for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, consider lyophilized powder under inert atmosphere. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular ion peak matches theoretical mass
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Acetate Content (IC)	≤ 15.0%
Single Impurity (HPLC)	≤ 2.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.