Description

L-Isoleucine Ethyl Ester Hydrochloride is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the precise construction of complex peptides and pharmaceutical intermediates. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications requiring high stereochemical purity and reliable supply.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) and peptide-based drugs.
• Peptide Synthesis (SPPS & Solution Phase): Used as a protected amino acid component in solid-phase and solution-phase peptide synthesis.
• Biochemical Research: Employed in proteomics research, enzyme substrate studies, and the development of metabolic probes.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material for the preparation of non-proteinogenic amino acids and other enantiomerically pure compounds.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances where specific stereochemistry is required.

Basic Information

Product Name	L-Isoleucine Ethyl Ester Hydrochloride
CAS No.	567-56-6
Molecular Formula	C8H18ClNO2
Molecular Weight	195.69 g/mol
Synonyms	L-Isoleucine ethyl ester HCl; Ethyl L-isoleucinate hydrochloride; (2S,3S)-2-Amino-3-methylpentanoic acid ethyl ester hydrochloride; H-Ile-OEt·HCl; Isoleucine ethyl ester monohydrochloride; (S,S)-Isoleucine ethyl ester hydrochloride; L-2-Amino-3-methylvaleric acid ethyl ester hydrochloride
EINECS	209-296-8

Quality Control

Our L-Isoleucine Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Specific Rotation [α]20/D	+35° to +40° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.