Description

Renanolone is a synthetic neurosteroid and a potent positive allosteric modulator of GABAA receptors. This compound is of significant interest in pharmaceutical research and development due to its potential neuroactive properties. It serves as a critical intermediate and reference standard for researchers and manufacturers in the life sciences sector, particularly those focused on central nervous system (CNS) therapeutics and neuroendocrinology.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced neuroactive steroid drugs and related compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control (QC/QA) of related pharmaceutical products.
• Biochemical Research: Employed in neuroscience studies to investigate the modulation of GABAergic signaling and its physiological effects.
• Neurosteroid Research: A vital tool for exploring the structure-activity relationships (SAR) of neurosteroids and their therapeutic potential.
• Active Pharmaceutical Ingredient (API) Development: Serves as a starting material or precursor in the development of new therapeutic agents targeting neurological and psychiatric conditions.

Basic Information

Product Name	Renanolone
CAS No.	565-99-1
Molecular Formula	C21H34O3
Molecular Weight	334.50 g/mol
Synonyms	3α-Hydroxy-5β-pregnan-20-one; 5β-Pregnan-3α-ol-20-one; 3α-Hydroxy-5β-pregnan-20-one; Pregnanolone; 5β-Pregnanolone; 3α,5β-Tetrahydroprogesterone; 3α-Hydroxy-5β-dihydroprogesterone; ELTANOLONE
EINECS	209-280-5

Quality Control

Our Renanolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents, supporting its use in research and development applications. Specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.