Description

3β-[(3-o-Methyl-2,6-Dideoxy-α-L-Arabino-Hexopyranosyl)Oxy]-12β,14-Dihydroxy-11-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a class of compounds with significant pharmacological activity. This compound is valued for its role as a critical reference standard and pharmaceutical intermediate in the research and development of cardiovascular therapeutics. It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in drug discovery and analytical method development.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of cardiac glycosides in active pharmaceutical ingredients (APIs) and finished drug products.
• Biochemical Research: Serves as a key reagent in studies investigating the mechanism of action of cardiotonic steroids on sodium-potassium ATPase pumps.
• Drug Discovery & Development: Acts as a crucial intermediate or lead compound in the synthesis and structural modification of novel cardiovascular agents.
• Quality Control Laboratories: Employed as a certified standard to ensure batch-to-batch consistency and purity of related pharmaceutical compounds.
• Metabolite Studies: Used in pharmacokinetic and metabolic pathway research to identify and characterize related metabolites.

Basic Information

Product Name	3β-[(3-o-Methyl-2,6-Dideoxy-α-L-Arabino-Hexopyranosyl)Oxy]-12β,14-Dihydroxy-11-Oxo-5β-Card-20(22)-Enolide
CAS No.	559-58-0
Molecular Formula	C30H44O9
Molecular Weight	548.67 g/mol
Synonyms	Gitoxigenin 3-O-α-L-digitoxoside; 3β-[(2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)oxy]-12β,14-dihydroxy-11-oxo-5β-card-20(22)-enolide; 3-O-Methyldigitoxigenin α-L-digitoxoside; 3-O-Methylgitoxigenin α-L-digitoxoside; 16-Formylgitoxigenin 3-O-α-L-digitoxoside (related); Strophanthidin derivative
EINECS	Contact for details

Quality Control

Our 3β-[(3-o-Methyl-2,6-Dideoxy-α-L-Arabino-Hexopyranosyl)Oxy]-12β,14-Dihydroxy-11-Oxo-5β-Card-20(22)-Enolide is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity and purity, aligning with pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every shipment to ensure full traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.