Description

2-Fluoro-5-(Trifluoromethyl)Aniline is a high-value fluorinated aromatic amine building block, essential for introducing both fluorine and aniline functionalities into complex molecular architectures. Its primary commercial value lies in enabling the synthesis of advanced agrochemicals and pharmaceuticals with enhanced biological activity and metabolic stability. This compound is critically needed by R&D and production chemists in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups improve lipophilicity and target binding.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in candidates targeting central nervous system (CNS) and oncology pathways.
• Liquid Crystal & OLED Material Synthesis: Serves as a starting material for creating fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Employed in the production of specialized, light-fast dyes and pigments for high-performance applications.
• Polymer Modification: Acts as a monomer or modifier to introduce aromatic amine groups into polymer chains, altering material properties.
• Cross-Coupling Reactions: Utilized in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethyl)Aniline
CAS No.	535-52-4
Molecular Formula	C7H5F4N
Molecular Weight	179.12 g/mol
Synonyms	2-Fluoro-5-(trifluoromethyl)benzenamine; 2-Fluoro-alpha,alpha,α-trifluoro-p-toluidine; 5-Amino-2-fluorobenzotrifluoride; Benzenamine, 2-fluoro-5-(trifluoromethyl)-; 2-Fluoro-5-trifluoromethylaniline; 2-Fluoro-α,α,α-trifluoro-p-toluidine; 2-Fluoro-5-(trifluoromethyl)phenylamine
EINECS	208-618-6

Quality Control

Our 2-Fluoro-5-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal purity and stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.