Description

D-Ethionine is the D-isomer of the sulfur-containing amino acid analog ethionine, a compound of significant interest in biochemical and pharmaceutical research. Its primary value lies in its role as a selective antagonist of L-methionine, allowing scientists to study metabolic pathways, methylation processes, and the biochemical mechanisms of liver toxicity and carcinogenesis. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic research sectors who require reliable, well-characterized biochemical tools.

Application

• Biochemical Research: Used as a specific antagonist of L-methionine to investigate amino acid metabolism, protein synthesis, and methylation dynamics in experimental models.
• Toxicology Studies: Employed in preclinical research to induce and study experimental models of hepatotoxicity and chemical carcinogenesis.
• Pharmaceutical Development: Serves as a key reference standard and intermediate in the development and quality control of related pharmaceutical compounds.
• Nutritional Science: Utilized in studies examining the effects of methionine deficiency and the metabolic consequences of amino acid imbalance.
• Enzyme Inhibition Studies: Acts as a substrate analog in enzymatic assays to study the specificity and kinetics of methionine-metabolizing enzymes.

Basic Information

Product Name	D-Ethionine
CAS No.	535-32-0
Molecular Formula	C6H13NO2S
Molecular Weight	163.24 g/mol
Synonyms	(2R)-2-Amino-4-(ethylthio)butyric acid; D-2-Amino-4-(ethylthio)butyric acid; (R)-Ethionine; D-α-Amino-γ-ethylmercaptobutyric acid; (R)-2-Amino-4-(ethylsulfanyl)butanoic acid; Ethionine D-form; D-ETH
EINECS	208-619-9

Quality Control

Our D-Ethionine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by IR spectroscopy and purity determination by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range provided on COA
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.