Description

3-Hydroxyglutamic Acid is a non-proteinogenic amino acid derivative of glutamic acid, featuring an additional hydroxyl group that imparts unique chemical reactivity and biological activity. This compound serves as a valuable chiral building block and intermediate in the synthesis of complex pharmaceuticals and bioactive molecules. It is of significant interest to research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of active pharmaceutical ingredients (APIs), particularly in neurologic and metabolic drug research.
• Biochemical Research: Used as a precursor or standard in studies of amino acid metabolism, enzyme mechanisms, and neurotransmitter pathways.
• Peptide Synthesis: Incorporation into custom peptides to modify structure, solubility, or biological activity for drug discovery and diagnostic applications.
• Nutritional Science Studies: Investigated for its potential role and effects in metabolic processes as a glutamic acid analog.
• Cosmetic Ingredient Development: Explored for use in advanced skincare formulations targeting cellular repair and moisturization.
• Agrochemical Research: Serves as a starting material for developing novel, biodegradable plant growth regulators or herbicides.

Basic Information

Product Name	3-Hydroxyglutamic Acid
CAS No.	533-62-0
Molecular Formula	C5H9NO5
Molecular Weight	163.13 g/mol
Synonyms	3-Hydroxy-L-glutamic Acid; (2S,3S)-3-Hydroxyglutamic Acid; β-Hydroxyglutamic Acid; 3-Hydroxyglutamate; HGA; 3-Hydroxy-1-aminopropane-1,3-dicarboxylic Acid
EINECS	208-576-2

Quality Control

Our 3-Hydroxyglutamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets exacting standards for research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.