Description

1H-Indole-2-Propanoic Acid, .Alpha.-Amino-, (.Alpha.S)- is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its unique indole side chain structure makes it a valuable chiral building block for the development of novel bioactive compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents or specialized intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, particularly in neuroscience and metabolic disorder research.
• Peptide Mimetics & Conjugates: Used in the synthesis of peptide analogs and bioconjugates to modulate biological activity and stability.
• Agrochemical Research: Serves as a precursor in the development of new plant growth regulators or specialized pesticides.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate metabolic pathways.
• Fine Chemical Synthesis: A versatile building block for constructing complex heterocyclic compounds and natural product analogs.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or reagent in stereoselective synthesis protocols.

Basic Information

Product Name	1H-Indole-2-Propanoic Acid, .Alpha.-Amino-, (.Alpha.S)-
CAS No.	533-42-6
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	(S)-α-Amino-1H-indole-2-propanoic Acid; (S)-2-Amino-3-(1H-indol-2-yl)propanoic Acid; L-α-Aminoindole-2-propionic Acid; (S)-Tryptophan-2-carboxylic Acid; 2-Carboxytryptophan; 2-(2-Amino-2-carboxyethyl)indole; (S)-1H-Indole-2-alanine; 533-42-6
EINECS	208-577-2

Quality Control

Our 1H-Indole-2-Propanoic Acid, .Alpha.-Amino-, (.Alpha.S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (S-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.