Description

2-Amino-3-(1H-Indazol-3-Yl)-Propionic Acid is a specialized non-proteinogenic amino acid derivative featuring an indazole heterocycle. This compound serves as a critical pharmacophore and synthetic building block in modern medicinal chemistry and drug discovery. It is primarily utilized by research institutions and pharmaceutical companies for the development of novel therapeutic agents, particularly in oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a constrained amino acid analog to study structure-activity relationships (SAR) and improve peptide metabolic stability.
• Bioconjugation & Probe Development: Serves as a handle for creating fluorescent probes or affinity tags for biological target identification.
• Chemical Biology Tool: Employed in fragment-based drug discovery and library synthesis for high-throughput screening.
• Academic Research: Used in university and institutional labs for fundamental studies in heterocyclic chemistry and amino acid derivatives.

Basic Information

Product Name	2-Amino-3-(1H-Indazol-3-Yl)-Propionic Acid
CAS No.	526-30-7
Molecular Formula	C10H11N3O2
Molecular Weight	205.21 g/mol
Synonyms	3-(1H-Indazol-3-yl)-L-alanine; 2-Amino-3-(1H-indazol-3-yl)propanoic acid; (S)-2-Amino-3-(1H-indazol-3-yl)propionic acid; L-3-(1H-Indazol-3-yl)alanine; 1H-Indazole-3-propanoic acid, α-amino-; 526-30-7; 3-Indazolylalanine; β-(3-Indazolyl)-L-alanine
EINECS	Contact for details

Quality Control

We supply 2-Amino-3-(1H-Indazol-3-Yl)-Propionic Acid in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict quality management protocols to ensure batch-to-batch consistency and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.