Description

Taurochenodeoxycholic Acid CAS NO 516-35-8 is a conjugated bile acid derivative, formed from the conjugation of chenodeoxycholic acid with taurine. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a key intermediate in bile acid metabolism and its potential therapeutic applications. It is primarily utilized by research institutions, pharmaceutical developers, and manufacturers of diagnostic reagents and high-purity biochemical standards.

Application

• Pharmaceutical Intermediate: Key starting material or reference standard in the synthesis of novel therapeutic agents targeting liver and metabolic disorders.
• Biochemical Research: Essential reagent for studying bile acid transport, cholestasis, and hepatobiliary physiology in in vitro and in vivo models.
• Diagnostic Reagent Manufacturing: Used in the production of calibration standards and kits for clinical diagnostics related to liver function and bile acid profiles.
• Cell Culture & Media Supplement: Employed in specialized cell culture applications to study its effects on cell signaling and membrane fluidity.
• Reference Standard: High-purity grade serves as a certified reference material (CRM) for analytical method development and quality control in laboratories.

Basic Information

Product Name	Taurochenodeoxycholic Acid
CAS No.	516-35-8
Molecular Formula	C26H45NO6S
Molecular Weight	499.71 g/mol
Synonyms	Chenodeoxycholyltaurine; TCDCA; 3α,7α-Dihydroxy-5β-cholan-24-oyltaurine; Taurochenodeoxycholate; N-[(3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl]taurine; 5β-Cholan-24-oic acid-3α,7α-diol, N-(2-sulfoethyl)amide; TDCA
EINECS	208-222-5

Quality Control

Our Taurochenodeoxycholic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can supply material compliant with various internal specifications for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.