Description

Chlorphenoxamine is an ethanolamine-derived antihistamine and anticholinergic agent, identified by CAS NO 511-46-6. This compound is valued for its specific pharmacological activity, making it a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical manufacturers and research institutions engaged in developing and producing treatments for conditions like Parkinson's disease and motion sickness.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of antihistamine and anticholinergic APIs.
• Active Pharmaceutical Ingredient (API): Used in the formulation of medications for Parkinson's disease and related movement disorders.
• Anticholinergic Agent: Employed in research and development of drugs to reduce muscle rigidity and tremors.
• Antihistamine Development: Serves as a core structure for developing new-generation allergy and motion sickness medications.
• Neurological Research: A valuable compound in preclinical and clinical studies targeting the central nervous system.
• Chemical Reference Standard: Used in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Chlorphenoxamine
CAS No.	511-46-6
Molecular Formula	C18H22ClNO
Molecular Weight	303.83 g/mol
Synonyms	Chlorphenoxamine; 2-[1-(4-Chlorophenyl)-1-phenylethoxy]-N,N-dimethylethanamine; Paryzine; Clorevan; Systral; Antihistaminicum; Histachlorphen; Phenoxene; Chlorphenoxaminum; N,N-Dimethyl-2-[1-phenyl-1-(4-chlorophenyl)ethoxy]ethanamine
EINECS	208-138-3

Quality Control

Our Chlorphenoxamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade pharmaceutical standards. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.