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3β-[(6-Deoxy-α-L-Talopyranosyl)Oxy]-5,11α,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide CAS NO 508-73-6


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CAS No.:508-73-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(6-Deoxy-α-L-Talopyranosyl)Oxy]-5,11α,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are essential for developing targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of cardiovascular drugs and novel bioactive molecules.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel cardiac glycosides and related therapeutic compounds.
  • Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase inhibition and cardiac cell signaling pathways.
  • Preclinical Development: Employed in the research and development phase for new cardiovascular drug candidates.
  • Academic Research: Utilized in university and institutional labs for chemical, pharmacological, and structure-activity relationship (SAR) studies.
  • Fine Chemical Synthesis: Acts as a chiral starting material or intermediate for the production of other specialized steroidal compounds.

Basic Information

Product Name 3β-[(6-Deoxy-α-L-Talopyranosyl)Oxy]-5,11α,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No. 508-73-6
Molecular Formula C29H42O10
Molecular Weight 550.64 g/mol
Synonyms Desglucouzarin; Uzarin; 3β-[(6-Deoxy-α-L-talopyranosyl)oxy]-5,11α,14-trihydroxy-19-oxo-5β-card-20(22)-enolide; 5β-Card-20(22)-enolide, 3-[(6-deoxy-α-L-talopyranosyl)oxy]-5,11α,14-trihydroxy-19-oxo-, (3β,5β,11α)-; Uzarigenin 3-O-α-L-talomethyloside
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Quality Control

Our 3β-[(6-Deoxy-α-L-Talopyranosyl)Oxy]-5,11α,14-Trihydroxy-19-Oxo-5β-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Loss on Drying ≤ 2.0%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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