Description

3β-[(3-o-Methyl-2,6-Dideoxy-β-D-Xylo-Hexopyranosyl)Oxy]-12β,14-Dihydroxy-11-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound matters for its role as a key building block in the research and development of novel cardioactive agents and other specialized therapeutic molecules. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on cardiovascular drug discovery and natural product chemistry.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel cardiac glycosides and related therapeutic compounds.
• Biochemical Research: Used as a reference standard or active probe in studies of sodium-potassium ATPase (Na+/K+-ATPase) inhibition and cardiac cell signaling pathways.
• Natural Product Chemistry: Employed in the semi-synthesis or structural modification of complex natural products derived from digitalis and other plant sources.
• Drug Discovery & Development: Acts as a scaffold or starting material for medicinal chemistry programs aimed at developing new treatments for heart failure and arrhythmias.
• Analytical Standard: Utilized as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.

Basic Information

Product Name	3β-[(3-o-Methyl-2,6-Dideoxy-β-D-Xylo-Hexopyranosyl)Oxy]-12β,14-Dihydroxy-11-Oxo-5β-Card-20(22)-Enolide
CAS No.	507-86-8
Molecular Formula	C30H44O9
Molecular Weight	548.67 g/mol
Synonyms	Gitoxigenin 3-O-methyl-2,6-dideoxy-β-D-xylo-hexopyranoside; 3β-[(3-O-Methyl-2,6-dideoxy-β-D-xylo-hexopyranosyl)oxy]-12β,14-dihydroxy-11-oxo-5β-card-20(22)-enolide; 3-O-Methyl-2,6-dideoxy-β-D-xylo-hexopyranosyl gitoxigenin; Gitoxigenin 3-O-methylxyloside; 3β-[(3-O-Methyl-2,6-dideoxy-β-D-xylo-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide-11-one
EINECS	Contact for details

Quality Control

Our 3β-[(3-o-Methyl-2,6-Dideoxy-β-D-Xylo-Hexopyranosyl)Oxy]-12β,14-Dihydroxy-11-Oxo-5β-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.