Description

3β,11α,14-Trihydroxy-12-Oxo-5β-Card-20(22)-Enolide is a high-purity cardenolide derivative, a key structural motif in bioactive natural products. This compound is valued for its role as a critical intermediate in pharmaceutical research and synthesis, particularly for the development of novel cardiac glycosides and other therapeutic agents. It serves the needs of advanced research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in steroid and natural product chemistry.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel cardiac glycosides and other steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and precursor in studies investigating sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and cardiac pharmacology.
• Natural Product Synthesis: Serves as a sophisticated starting material or intermediate in the total or semi-synthesis of complex cardenolides and bufadienolides.
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control of related pharmaceutical compounds.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to develop new therapeutic agents with potential cardioprotective or anticancer properties.

Basic Information

Product Name	3β,11α,14-Trihydroxy-12-Oxo-5β-Card-20(22)-Enolide
CAS No.	507-84-6
Molecular Formula	C₂₃H₃₂O₆
Molecular Weight	404.50 g/mol
Synonyms	12-Oxocardenolide; 3β,11α,14-Trihydroxy-12-oxo-5β-card-20(22)-enolide; 12-Oxo-3β,11α,14-trihydroxy-5β-card-20(22)-enolide; 12-Oxocard-20(22)-enolide-3β,11α,14-triol; 3β,11α,14-Trihydroxy-12-oxocard-20(22)-enolide; 12-Oxocarden; Card-20(22)-enolide-3β,11α,14-triol, 12-oxo-
EINECS	Contact for details

Quality Control

Our 3β,11α,14-Trihydroxy-12-Oxo-5β-Card-20(22)-Enolide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.