Description

Bradykinin CAS NO 58-82-2 is a potent, endogenous nonapeptide hormone that plays a critical role in the regulation of blood pressure, inflammation, and pain signaling pathways. Its primary commercial value lies in its use as a high-purity reference standard and active pharmaceutical ingredient (API) for research and diagnostic applications. This peptide is essential for pharmaceutical R&D, clinical diagnostics, and academic research focused on cardiovascular physiology, inflammatory diseases, and neurobiology.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, MS) in quality control laboratories.
• Biomedical Research: Critical for in vitro and in vivo studies investigating the kallikrein-kinin system, vascular permeability, and inflammatory responses.
• Diagnostic Kit Manufacturing: Serves as a key component in the production of immunoassay kits for measuring bradykinin and related peptides.
• Drug Discovery & Development: Employed as a tool compound for screening and characterizing potential antagonists targeting bradykinin receptors (B1 and B2).
• Academic & Clinical Studies: Utilized to explore its role in conditions like hereditary angioedema, sepsis, hypertension, and chronic pain.

Basic Information

Product Name	Bradykinin
CAS No.	58-82-2
Molecular Formula	C50H73N15O11
Molecular Weight	1060.21 g/mol
Synonyms	Bradykinin; Kallidin I; BRS 640; Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg; H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; Kinin-9; 9-L-Bradykinin; Polypeptide BRS 640
EINECS	200-398-8

Quality Control

Our Bradykinin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by mass spectrometry and HPLC purity analysis, to ensure it meets the stringent requirements for research and diagnostic use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.