Description

2-Amino-4,6-Dichloropyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, where the amino group and chlorine atoms provide distinct handles for selective chemical transformations. This compound is essential for research and production chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, antiviral agents, and kinase inhibitors.
• Agrochemical Synthesis: Building block for creating herbicides, fungicides, and plant growth regulators.
• Material Science: Used in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Dye & Pigment Manufacturing: Intermediate for producing specialized heterocyclic dyes and colorants.
• Chemical Research: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Cross-Coupling Reactions: Serves as a substrate in Buchwald-Hartwig amination and Suzuki-Miyaura coupling reactions.

Basic Information

Product Name	2-Amino-4,6-Dichloropyrimidine
CAS No.	56-05-3
Molecular Formula	C4H3Cl2N3
Molecular Weight	163.99 g/mol
Synonyms	4,6-Dichloro-2-pyrimidinamine; 4,6-Dichloropyrimidin-2-amine; 2-Pyrimidinamine, 4,6-dichloro-; NSC 403697; ACDL 2; 2-ADCP; 4,6-Dichloro-2-aminopyrimidine
EINECS	200-254-6

Quality Control

Our 2-Amino-4,6-Dichloropyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	195 - 200 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.