Description

Trifluorothymine is a fluorinated pyrimidine nucleobase analog, a key building block in medicinal chemistry and advanced materials science. Its unique structure, featuring fluorine atoms at the 5-position, imparts significant metabolic stability and lipophilicity, making it a valuable intermediate for the synthesis of novel pharmaceuticals and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing next-generation antiviral agents, anticancer drugs, and high-performance materials.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of fluorinated nucleoside analogs used as antiviral and anticancer agents.
• Agrochemical Research: Serves as a building block for developing novel herbicides and pesticides with enhanced activity and environmental profile.
• Biochemical Research: Used in studies of enzyme mechanisms, DNA/RNA metabolism, and as a tool compound in molecular biology.
• Material Science: Acts as a monomer or modifier in the development of specialty polymers and advanced organic electronic materials.
• Diagnostic Reagents: Employed in the manufacture of probes and labels for diagnostic assays and imaging.

Basic Information

Product Name	Trifluorothymine
CAS No.	54-20-6
Molecular Formula	C5H3F3N2O2
Molecular Weight	180.08 g/mol
Synonyms	5-Trifluoromethyluracil; 5-Trifluoromethyl-2,4(1H,3H)-pyrimidinedione; 5-(Trifluoromethyl)uracil; 2,4-Dihydroxy-5-(trifluoromethyl)pyrimidine; NSC 38280; α,α,α-Trifluorothymine; 5-CF3-Uracil
EINECS	200-197-7

Quality Control

Our Trifluorothymine is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) documenting all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.