Description

Asn-Arg-Val-Tyr-Val-His-Pro-Phe CAS NO 53-73-6 is a synthetic octapeptide, specifically the Angiotensin II sequence, which serves as a critical biochemical tool and reference standard. This compound is essential for research into the renin-angiotensin system, cardiovascular physiology, and hypertension. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of diagnostic kits and biochemical reagents.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of the renin-angiotensin-aldosterone system (RAAS).
• Pharmaceutical Development: Serves as a key intermediate or analytical standard in the development of antihypertensive drugs and related therapeutics.
• Diagnostic Reagents: Employed in the production and calibration of immunoassay kits for measuring angiotensin II levels in biological samples.
• Enzyme Substrate: Acts as a specific substrate for studying the activity of angiotensin-converting enzyme (ACE) and other proteases.
• Cell Signaling Studies: Utilized in vitro and in vivo to investigate vascular contraction, aldosterone secretion, and other physiological responses mediated by the AT1 receptor.
• Quality Control: Functions as a system suitability standard in analytical laboratories for method validation and equipment calibration.

Basic Information

Product Name	Asn-Arg-Val-Tyr-Val-His-Pro-Phe
CAS No.	53-73-6
Molecular Formula	C₄₉H₆₉N₁₅O₁₂
Molecular Weight	1046.2 g/mol
Synonyms	Angiotensin II; Angiotensin II (human); Asp-Arg-Val-Tyr-Val-His-Pro-Phe; H-Asp-Arg-Val-Tyr-Val-His-Pro-Phe-OH; DRVYVHPF; 1-L-Asparaginyl-5-L-valyl-8-L-phenylalanyl angiotensin; Hypertensin; All natural L-Angiotensin II
EINECS	200-191-8

Quality Control

Our Asn-Arg-Val-Tyr-Val-His-Pro-Phe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content (Amino Acid Analysis)	≥ 80.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.