Description

7-(2-Methoxyethyl)-3-Methyl-8-(Piperazin-1-Yl)-3,7-Dihydro-1H-Purine-2,6-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its purine-based molecular structure. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly in oncology and central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential adenosine receptor antagonists and other purine-based active pharmaceutical ingredients (APIs).
• Oncology Research: Used in the development of novel small-molecule inhibitors targeting specific cancer pathways.
• CNS Drug Discovery: Serves as a core scaffold for research into treatments for neurological and psychiatric conditions.
• Biochemical Research: Employed as a reference standard or probe in enzymatic and receptor binding studies.
• Preclinical Development: Utilized for pharmacokinetic, pharmacodynamic, and toxicology studies of new chemical entities.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific research programs.

Basic Information

Product Name	7-(2-Methoxyethyl)-3-Methyl-8-(Piperazin-1-Yl)-3,7-Dihydro-1H-Purine-2,6-Dione
CAS No.	499986-59-3
Molecular Formula	C13H20N6O3
Molecular Weight	308.34 g/mol
Synonyms	8-(1-Piperazinyl)-7-(2-methoxyethyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; 3-Methyl-7-(2-methoxyethyl)-8-(piperazin-1-yl)-1H-purine-2,6(3H,7H)-dione; 7-(2-Methoxyethyl)-3-methyl-8-(piperazin-1-yl)-3,7-dihydropurine-2,6-dione; 8-Piperazin-1-yl-7-(2-methoxyethyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione; Purine-2,6-dione, 3,7-dihydro-7-(2-methoxyethyl)-3-methyl-8-(1-piperazinyl)-; Adenosine Receptor Antagonist Intermediate
EINECS	Contact for details

Quality Control

Our 7-(2-Methoxyethyl)-3-Methyl-8-(Piperazin-1-Yl)-3,7-Dihydro-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring a reliable supply for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.