Description

2-(Piperidin-4-Yloxy)Pyrimidine is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a pyrimidine ring linked to a piperidine moiety via an ether bridge, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research institutions and pharmaceutical developers engaged in medicinal chemistry and drug discovery programs. Its reliable quality and consistent supply are essential for accelerating R&D timelines in these high-value sectors.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and herbicides due to its bioactive heterocyclic core.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A fundamental starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-(Piperidin-4-Yloxy)Pyrimidine
CAS No.	499240-48-1
Molecular Formula	C9H13N3O
Molecular Weight	179.22 g/mol
Synonyms	4-[(Pyrimidin-2-yl)oxy]piperidine; 2-(4-Piperidyloxy)pyrimidine; 2-Pyrimidinyl 4-piperidinyl ether; Piperidine, 4-[(2-pyrimidinyl)oxy]-; 4-(Pyrimidin-2-yloxy)piperidine
EINECS	Contact for details

Quality Control

Every batch of 2-(Piperidin-4-Yloxy)Pyrimidine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.