Description

Phenol, 2-(1-Fluorocyclopropyl)- (9Ci) is a specialized fluorinated phenol derivative characterized by its unique cyclopropyl ring adjacent to the phenolic hydroxyl group. This structural motif makes it a valuable high-purity synthetic intermediate for constructing complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry and crop protection science, where the introduction of fluorine and strained ring systems can modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery programs.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorocyclopropyl group for enhanced efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers and advanced materials with tailored surface properties.
• Ligand Synthesis: Employed in organometallic chemistry for creating sophisticated ligands used in catalysis and sensor development.
• Fluorine Chemistry Studies: A valuable reference compound for academic and industrial research exploring the effects of fluorinated alicyclic structures on chemical reactivity and stability.

Basic Information

Item	Detail
Product Name	Phenol, 2-(1-Fluorocyclopropyl)- (9Ci)
CAS No.	499234-78-5
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	2-(1-Fluorocyclopropyl)phenol; 1-Fluoro-1-(2-hydroxyphenyl)cyclopropane; o-(1-Fluorocyclopropyl)phenol; (1-Fluorocyclopropyl)phenol; Phenol, (1-fluorocyclopropyl)-; Fluorocyclopropylphenol; FCPP (abbrev.)
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system aligned with cGMP principles for advanced intermediates. Every batch of Phenol, 2-(1-Fluorocyclopropyl)- (9Ci) is subjected to comprehensive analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to ensure traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.