Description

Ethyl 4-(2-Chloropyrimidin-4-Yl)Benzoate is a high-value, multi-functional chemical intermediate with a distinct pyrimidine-benzoate core structure. This compound is critical for the synthesis of advanced pharmaceutical ingredients and agrochemicals, offering a versatile scaffold for further functionalization. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Utilized in the development of molecular probes and diagnostic agents due to its modifiable halogen and ester functional groups.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences sector.

Basic Information

Product Name	Ethyl 4-(2-Chloropyrimidin-4-Yl)Benzoate
CAS No.	499195-60-7
Molecular Formula	C₁₃H₁₁ClN₂O₂
Molecular Weight	262.69 g/mol
Synonyms	Ethyl 4-(2-chloropyrimidin-4-yl)benzoate; 4-(2-Chloro-4-pyrimidinyl)benzoic Acid Ethyl Ester; Benzoic acid, 4-(2-chloro-4-pyrimidinyl)-, ethyl ester; 2-Chloro-4-(4-ethoxycarbonylphenyl)pyrimidine; 499195-60-7; Ethyl p-(2-chloropyrimidin-4-yl)benzoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(2-Chloropyrimidin-4-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material that meets stringent internal standards, suitable for use in GMP-regulated synthesis upon request and qualification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.