Description

6-Bromo-3-Chloropyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require precise and reliable intermediates for their synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for creating specialized organic electronic materials, ligands for catalysis, and advanced polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in drug discovery programs.
• Custom Synthesis: Provides a starting point for contract manufacturing organizations (CMOs) to produce tailored intermediates for client-specific projects.

Basic Information

Product Name	6-Bromo-3-Chloropyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	499190-16-8
Molecular Formula	C7H3BrClN3O2
Molecular Weight	276.47 g/mol
Synonyms	6-Bromo-3-chloro-2-pyrazolo[1,5-a]pyrimidinecarboxylic acid; 6-Bromo-3-chloropyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 2-Pyrazolo[1,5-a]pyrimidinecarboxylic acid, 6-bromo-3-chloro-; 499190-16-8; 6-Br-3-Cl-Pyrazolo[1,5-a]pyrimidine-2-COOH; 6-Bromo-3-chloro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 3-Chloro-6-bromopyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloropyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.