Description

3,5-Dibromo-2-Fluorobenzyl Alcohol is a halogenated benzyl alcohol derivative serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of bromine and fluorine atoms, which enable selective functionalization for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine and bromine substituents for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Intermediate in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atoms make it a valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Fluorine Chemistry Studies: Used as a model compound in methodological development for introducing and manipulating fluorine-containing groups.

Basic Information

Product Name	3,5-Dibromo-2-Fluorobenzyl Alcohol
CAS No.	497181-27-8
Molecular Formula	C7H5Br2FO
Molecular Weight	267.92 g/mol
Synonyms	(3,5-Dibromo-2-fluorophenyl)methanol; 2-Fluoro-3,5-dibromobenzyl Alcohol; 1-(3,5-Dibromo-2-fluorophenyl)methanol; α,3,5-Tribromo-2-fluorotoluene (deprecated); 3,5-Dibromo-2-fluoro-benzenemethanol
EINECS	Contact for details

Quality Control

Our 3,5-Dibromo-2-Fluorobenzyl Alcohol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.