Description

Pyrimidine, 2,2-Difluorohexahydro-1,3-Dimethyl- (9Ci) is a specialized fluorinated heterocyclic compound that serves as a valuable building block in advanced organic synthesis. Its unique structure, featuring a saturated pyrimidine core with fluorine substituents, makes it a critical intermediate for developing novel pharmaceuticals and agrochemicals. This high-purity intermediate is essential for research and development chemists in the life sciences and fine chemical industries seeking to introduce fluorine atoms to modulate the biological activity and metabolic stability of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorinated pyrimidine moiety can enhance efficacy and environmental profile.
• Fluorination Chemistry Research: Serves as a model compound or precursor in methodological studies for introducing difluoromethylene groups into complex molecular architectures.
• Ligand and Catalyst Development: Potential utility in designing novel ligands for catalysis or as a scaffold in material science for electronic or optical applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated heterocycles.

Basic Information

Product Name	Pyrimidine, 2,2-Difluorohexahydro-1,3-Dimethyl- (9Ci)
CAS No.	497181-15-4
Molecular Formula	C7H12F2N2
Molecular Weight	162.18 g/mol
Synonyms	2,2-Difluoro-1,3-dimethylhexahydropyrimidine; 1,3-Dimethyl-2,2-difluoroperhydropyrimidine; Hexahydro-2,2-difluoro-1,3-dimethylpyrimidine; 2,2-Difluoro-1,3-dimethylhexahydro-1,3-diazine; 1,3-Dimethyl-2,2-difluorohexahydropyrimidine; 2,2-Difluoro-1,3-dimethyltetrahydropyrimidine (ambiguous); N,N'-Dimethyl-2,2-difluorotetrahydro-1,3-diazine
EINECS	Contact for details

Quality Control

Every batch of Pyrimidine, 2,2-Difluorohexahydro-1,3-Dimethyl- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development projects with custom purity grades and analytical method development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.