Description

n-Pyrimidin-2-Yl(4-(Trifluoromethyl)Phenyl)Formamide is a specialized organic compound featuring a pyrimidine core linked to a trifluoromethylphenyl group via a formamide bridge. This molecular architecture makes it a high-value intermediate for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for antiviral, anticancer, or central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine and trifluoromethyl motifs.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical companies offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	n-Pyrimidin-2-Yl(4-(Trifluoromethyl)Phenyl)Formamide
CAS No.	497059-99-1
Molecular Formula	C12H8F3N3O
Molecular Weight	267.21 g/mol
Synonyms	N-(Pyrimidin-2-yl)-4-(trifluoromethyl)benzamide; 4-(Trifluoromethyl)-N-(2-pyrimidinyl)benzamide; 2-Pyrimidinamine, N-[4-(trifluoromethyl)phenyl]-, 1-oxide; Benzamide, N-(2-pyrimidinyl)-4-(trifluoromethyl)-; N-(Pyrimidin-2-yl)-[4-(trifluoromethyl)phenyl]formamide
EINECS	Contact for details

Quality Control

Our n-Pyrimidin-2-Yl(4-(Trifluoromethyl)Phenyl)Formamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.