Description

N,n-Dibenzyl-2-Chloro-9-Methyl-9H-Purin-6-Amine CAS NO 496955-48-7 is a high-purity, synthetic purine derivative, a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of novel pharmaceutical agents, particularly in the research of kinase inhibitors and other targeted therapeutics. It is primarily required by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel purine-based drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of potential therapeutic compounds.
• Kinase Inhibitor Development: Serves as a core structural component in the research and development of ATP-competitive kinase inhibitors.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme mechanisms and cellular signaling processes.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-fidelity, functionalized purine intermediates.

Basic Information

Product Name	N,n-Dibenzyl-2-Chloro-9-Methyl-9H-Purin-6-Amine
CAS No.	496955-48-7
Molecular Formula	C20H18ClN5
Molecular Weight	363.84 g/mol
Synonyms	2-Chloro-N,N-dibenzyl-9-methyl-9H-purin-6-amine; 2-Chloro-9-methyl-N,N-bis(phenylmethyl)-9H-purin-6-amine; 9-Methyl-2-chloro-N,N-dibenzyl-9H-purin-6-amine; DBZ-CL-9M-PA; Purine-6-amine, 2-chloro-9-methyl-N,N-bis(phenylmethyl)-9H-; N,N-Dibenzyl-2-chloro-9-methyl-9H-purin-6-amine
EINECS	Contact for details

Quality Control

Our N,n-Dibenzyl-2-Chloro-9-Methyl-9H-Purin-6-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.