Description

6-Bromo-D-Tryptophan is a halogenated derivative of the essential amino acid tryptophan, featuring a bromine atom at the 6-position of the indole ring. This specific modification makes it a valuable chiral building block and intermediate for the synthesis of complex bioactive molecules. It is particularly sought after by research and development teams in the pharmaceutical and biotechnology sectors. The compound's defined stereochemistry and functional groups enable its use in creating novel peptide-based therapeutics, enzyme inhibitors, and other pharmacologically active agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in oncology and neurology.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a brominated tryptophan residue, modifying peptide structure and activity.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme inhibition assays.
• Proteomics & Labeling: Potential use as a heavy-atom label in X-ray crystallography or as a tag in mass spectrometry-based proteomic studies.
• Agrochemical Research: An intermediate in the development of novel plant growth regulators or pesticides with specific biological activity.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	6-Bromo-D-Tryptophan
CAS No.	496930-10-0
Molecular Formula	C₁₁H₁₁BrN₂O₂
Molecular Weight	283.12 g/mol
Synonyms	(2R)-2-Amino-3-(6-bromo-1H-indol-3-yl)propanoic acid; D-6-Bromotryptophan; (R)-6-Bromotryptophan; 6-Bromo-D-Trp; 6-Br-D-Trp-OH; 6-Bromo-(R)-Tryptophan; 6-Bromotryptophan, D-; 6-Bromo-DL-Tryptophan (related, but racemic)
EINECS	Contact for details

Quality Control

Our 6-Bromo-D-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC), enantiomeric excess, and related substances is provided with every shipment. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.