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H-Tyr-Cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe) CAS NO 496849-46-8


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CAS No.:496849-46-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

H-Tyr-Cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe) is a synthetic, cyclic peptide derivative with a complex and specific amino acid sequence. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the study of peptide-based therapeutics and diagnostic agents. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in the development of novel drug candidates, receptor-binding studies, and biochemical assays.

Application

  • Pharmaceutical Research: Serves as a key intermediate or reference standard in the development of novel peptide-based drugs targeting G-protein-coupled receptors (GPCRs).
  • Biochemical Assays: Used as a high-purity ligand or substrate in receptor-binding studies, enzyme inhibition tests, and signal transduction pathway analysis.
  • Diagnostic Development: Potential application in the formulation of diagnostic kits for research purposes, utilizing its specific biological activity.
  • Academic Research: Employed in university and institutional labs for studying peptide structure-activity relationships (SAR) and molecular biology.
  • Preclinical Studies: Utilized in animal model research to investigate pharmacokinetics, efficacy, and safety profiles of peptide analogues.

Basic Information

Product Name H-Tyr-Cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe)
CAS No. 496849-46-8
Molecular Formula C86H112N20O15
Molecular Weight 1641.94 g/mol
Synonyms Cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe-Tyr); c[D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe-Tyr]; Somatostatin analogue (cyclic); Cyclic peptide 496849-46-8; H-Tyr-c[D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe]; Cyclo(D-2,4-diaminobutyryl-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe-Tyr)
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Quality Control

Our H-Tyr-Cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe) is manufactured under strict quality systems suitable for research and development applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure consistent quality and batch-to-batch reproducibility. Certificates of Analysis (COA) with detailed chromatographic data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 2.0%
Water Content (KF) ≤ 5.0%
Peptide Content ≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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