Description

Ethyl 4-[({[(4-Amino-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetyl}amino)methyl]benzoate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, particularly those targeting kinase pathways. Pharmaceutical R&D and fine chemical synthesis companies require this material for developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for oncology and other therapeutic areas.
• Kinase Inhibitor Research: Serves as a core scaffold for the development and optimization of small molecule kinase inhibitors.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Biochemical Research: Employed as a reference standard or tool compound in biochemical and pharmacological assays.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Item	Information
Product Name	Ethyl 4-[({[(4-Amino-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetyl}amino)methyl]benzoate
CAS No.	496028-85-4
Molecular Formula	C23H24N4O3S2
Molecular Weight	468.59 g/mol
Synonyms	Ethyl 4-[[2-[(4-Amino-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)thio]acetamido]methyl]benzoate; 4-[[[2-[(4-Amino-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio]acetyl]amino]methyl]benzoic Acid Ethyl Ester; Benzoic acid, 4-[[[2-[(4-amino-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)thio]acetyl]amino]methyl]-, ethyl ester; 496028-85-4; Ethyl 4-((((4-amino-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamido)methyl)benzoate
EINECS	Contact for details

Quality Control

Our Ethyl 4-[({[(4-Amino-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetyl}amino)methyl]benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.