Description

tert-Butyl 3-Fluoro-4-Methylphenylcarbamate is a high-purity, advanced pharmaceutical intermediate used in the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a versatile building block for introducing specific functional groups into target molecules. It is primarily utilized by pharmaceutical manufacturers and R&D organizations focused on creating novel therapeutic agents, particularly in the areas of oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors for antiviral and anticancer applications.
• Agrochemical Intermediate: Employed in the research and development of advanced pesticides and herbicides.
• Material Science: Used in the synthesis of specialty polymers and advanced organic materials.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	tert-Butyl 3-Fluoro-4-Methylphenylcarbamate
CAS No.	494789-04-7
Molecular Formula	C12H16FNO2
Molecular Weight	225.26 g/mol
Synonyms	Carbamic acid, N-(3-fluoro-4-methylphenyl)-, 1,1-dimethylethyl ester; tert-Butyl (3-fluoro-4-methylphenyl)carbamate; N-(tert-Butoxycarbonyl)-3-fluoro-4-methylaniline; 3-Fluoro-4-methylphenylcarbamic acid tert-butyl ester; BOC-3-fluoro-4-methylaniline; N-Boc-3-fluoro-4-methylaniline; 1,1-Dimethylethyl N-(3-fluoro-4-methylphenyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Fluoro-4-Methylphenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong acids and bases. The product is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.