Description

2-(1-Methylpiperidin-4-Yloxy)-5-(Trifluoromethyl)Benzenamine is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethyl-substituted aniline structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the trifluoromethyl and piperidine motifs.
• Organic Synthesis Building Block: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Research: Investigated as a component in the synthesis of specialty polymers and advanced organic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2-(1-Methylpiperidin-4-Yloxy)-5-(Trifluoromethyl)Benzenamine
CAS No.	494777-68-3
Molecular Formula	C13H17F3N2O
Molecular Weight	274.28 g/mol
Synonyms	5-(Trifluoromethyl)-2-[(1-methyl-4-piperidinyl)oxy]benzenamine; 2-[(1-Methyl-4-piperidinyl)oxy]-5-(trifluoromethyl)aniline; 2-(1-Methylpiperidin-4-yloxy)-5-(trifluoromethyl)aniline; 5-(Trifluoromethyl)-2-(1-methylpiperidin-4-yloxy)aniline; Benzenamine, 2-(1-methyl-4-piperidinyl)oxy-5-(trifluoromethyl)-; 494777-68-3; 2-(N-Methyl-4-piperidyloxy)-5-trifluoromethylaniline
EINECS	Contact for details

Quality Control

Every batch of 2-(1-Methylpiperidin-4-Yloxy)-5-(Trifluoromethyl)Benzenamine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.