Description

2-(3-Trifluoromethylphenyl)Malondialdehyde is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its unique structure, featuring both a reactive malondialdehyde moiety and a trifluoromethylphenyl group, which is highly valuable for introducing fluorine atoms and specific reactivity into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a building block for synthesizing fluorinated polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Synthesis: Employed in organic reactions such as Knoevenagel condensations and as a precursor for heterocyclic compounds like pyrazoles and pyrimidines.
• Fluorine Chemistry: Acts as a versatile scaffold for introducing the pharmacologically beneficial trifluoromethyl group into complex molecular architectures.

Basic Information

Product Name	2-(3-Trifluoromethylphenyl)Malondialdehyde
CAS No.	493036-49-0
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	3-(Trifluoromethyl)benzylidenepropanedial; 2-(3-(Trifluoromethyl)phenyl)malonaldehyde; 3-(Trifluoromethyl)phenylmalondialdehyde; 2-(α,α,α-Trifluoro-m-tolyl)malondialdehyde; (3-Trifluoromethylphenyl)propanedial; m-Trifluoromethylphenylmalondialdehyde; 1,1'-[3-(Trifluoromethyl)phenyl]malondialdehyde
EINECS	Contact for details

Quality Control

Our 2-(3-Trifluoromethylphenyl)Malondialdehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.