Description

2,4(1H,3H)-Pyrimidinedione,Dihydro-1,5-Dimethyl-,(5R)-(9Ci) is a chiral, dihydropyrimidine derivative with significant potential as a key synthetic intermediate in advanced organic chemistry. This compound, identified by CAS number 492442-60-1, is valued for its stereochemical purity and functionalized heterocyclic core, which serves as a versatile building block for complex molecular architectures. It is primarily sought by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), nucleoside analogs, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the research and development of novel therapeutic agents, particularly in antiviral and anticancer drug discovery programs.
• Nucleoside/Nucleotide Chemistry: Serves as a precursor or analog in the synthesis of modified nucleosides and nucleotides for biochemical research and prodrug development.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective synthesis routes to construct complex molecules with defined chirality.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new reaction pathways involving pyrimidine scaffolds.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value, low-volume products requiring precise chemical structures.

Basic Information

Product Name	2,4(1H,3H)-Pyrimidinedione,Dihydro-1,5-Dimethyl-,(5R)-(9Ci)
CAS No.	492442-60-1
Molecular Formula	C6H10N2O2
Molecular Weight	142.16 g/mol
Synonyms	(5R)-1,5-Dimethyl-1,4,5,6-tetrahydropyrimidine-2,4(1H,3H)-dione; (5R)-1,5-Dimethyldihydropyrimidine-2,4(1H,3H)-dione; (R)-1,5-Dimethyl-1,4,5,6-tetrahydropyrimidine-2,4(1H,3H)-dione; Dihydro-1,5-dimethyl-2,4(1H,3H)-pyrimidinedione, (5R)-; 1,5-Dimethyl-1,4,5,6-tetrahydropyrimidine-2,4(1H,3H)-dione (enantiomer); 492442-60-1; (R)-Enantiomer of Dihydro-1,5-dimethyl-2,4(1H,3H)-pyrimidinedione
EINECS	Contact for details

Quality Control

Our production of 2,4(1H,3H)-Pyrimidinedione,Dihydro-1,5-Dimethyl-,(5R)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chiral purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR for structural confirmation, and standard purity assays. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral purity is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.