Description

4-Chloro-5-(4-Phenoxyphenyl)-7-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily required by pharmaceutical R&D organizations and fine chemical manufacturers engaged in developing kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and immunology research.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and optimizing compounds that modulate specific kinase activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore new chemical entities and improve drug-like properties.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds.
• Biochemical Tool Compound: May be utilized in biological assays to study cellular pathways and validate novel drug targets.

Basic Information

Product Name	4-Chloro-5-(4-Phenoxyphenyl)-7-(1,4-Dioxaspiro[4.5]Decan-8-Yl)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	490030-16-5
Molecular Formula	C28H26ClN3O3
Molecular Weight	487.98 g/mol
Synonyms	4-Chloro-5-(4-phenoxyphenyl)-7-(1,4-dioxaspiro[4.5]decan-8-yl)-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-(4-phenoxyphenyl)-7-(1,4-dioxaspiro[4.5]decan-8-yl)-; CAS 490030-16-5; 4-Chloro-5-(4-phenoxyphenyl)-7-(1,4-dioxaspiro[4.5]decan-8-yl)-7H-pyrrolo[2,3-d]pyrimidine; 490030-16-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound should be handled under an inert atmosphere if prolonged exposure is anticipated during use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.