Description

Ethyl [2-({[(3,5,6-Trimethyl-4-Oxo-3,4-Dihydrothieno[2,3-D]Pyrimidin-2-Yl)Sulfanyl]Acetyl}Amino)-1,3-Thiazol-4-Yl]Acetate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in the areas of oncology and metabolic diseases.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of proprietary drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Integral in the production route for potential kinase inhibitors or other targeted therapies.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme interactions and cellular processes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ethyl [2-({[(3,5,6-Trimethyl-4-Oxo-3,4-Dihydrothieno[2,3-D]Pyrimidin-2-Yl)Sulfanyl]Acetyl}Amino)-1,3-Thiazol-4-Yl]Acetate
CAS No.	489413-78-7
Molecular Formula	C19H20N4O4S3
Molecular Weight	464.58 g/mol
Synonyms	Ethyl 2-[[2-[(3,5,6-trimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)sulfanyl]acetyl]amino]-1,3-thiazole-4-acetate; 4-Thiazoleacetic acid, 2-[[2-[(3,5,6-trimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)thio]acetyl]amino]-, ethyl ester; CAS 489413-78-7; Thienopyrimidinyl-thiazole acetate derivative; Advanced heterocyclic intermediate 489413-78-7.
EINECS	Contact for details

Quality Control

Our Ethyl [2-({[(3,5,6-Trimethyl-4-Oxo-3,4-Dihydrothieno[2,3-D]Pyrimidin-2-Yl)Sulfanyl]Acetyl}Amino)-1,3-Thiazol-4-Yl]Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.