Description

n-Methyl-5-(4-Methylphenyl)-7-(Trifluoromethyl)-n-[(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Methyl]Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide CAS NO 489410-54-0 is a high-purity, complex heterocyclic compound featuring a pyrazolo[1,5-a]pyrimidine core. This molecule is of significant commercial interest as a key pharmaceutical intermediate or advanced research chemical for drug discovery programs. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for kinase inhibitors or other targeted therapies.
• Medicinal Chemistry Research: Used as a scaffold or lead compound in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Organic Synthesis Reference Standard: Provides a high-purity standard for analytical method development and validation in QC laboratories.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for advanced studies in heterocyclic chemistry and drug design.

Basic Information

Product Name	n-Methyl-5-(4-Methylphenyl)-7-(Trifluoromethyl)-n-[(1,3,5-Trimethyl-1H-Pyrazol-4-Yl)Methyl]Pyrazolo[1,5-A]Pyrimidine-3-Carboxamide
CAS No.	489410-54-0
Molecular Formula	C25H25F3N6O
Molecular Weight	482.50 g/mol
Synonyms	N-Methyl-5-(p-tolyl)-7-(trifluoromethyl)-N-[(1,3,5-trimethyl-1H-pyrazol-4-yl)methyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide; 489410-54-0; Pyrazolo[1,5-a]pyrimidine-3-carboxamide, N-methyl-5-(4-methylphenyl)-7-(trifluoromethyl)-N-[(1,3,5-trimethyl-1H-pyrazol-4-yl)methyl]-; UNII-8G5V6U4T8F; 8G5V6U4T8F; SCHEMBL218084; BDBM50389325; AKOS040757623; ZINC000257830587
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to ensure identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support our clients' regulatory needs with traceable documentation and can tailor specifications to meet GMP or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.