Description

2-{[2-(2-Hydroxyethoxy)Ethyl]Amino}-3-{[4-Oxo-3-(2-Phenylethyl)-2-Thioxo-1,3-Thiazolidin-5-Ylidene]Methyl}-4H-Pyrido[1,2-A]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its potential role as a key building block in synthesizing novel therapeutic agents. It is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially in areas requiring specialized nitrogen and sulfur-containing heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• API Development: Employed in the research and process development stages for new Active Pharmaceutical Ingredients (APIs), particularly those with thiazolidinone and pyridopyrimidinone cores.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe to study specific enzyme interactions or biological mechanisms.
• Fine Chemical Synthesis: Acts as a specialized reagent for constructing complex molecular architectures in advanced organic synthesis.

Basic Information

Item	Details
Product Name	2-{[2-(2-Hydroxyethoxy)Ethyl]Amino}-3-{[4-Oxo-3-(2-Phenylethyl)-2-Thioxo-1,3-Thiazolidin-5-Ylidene]Methyl}-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	489404-52-6
Molecular Formula	C26H26N4O4S2
Molecular Weight	522.64 g/mol
Synonyms	2-{[2-(2-Hydroxyethoxy)ethyl]amino}-3-{[4-oxo-3-(2-phenylethyl)-2-thioxo-1,3-thiazolidin-5-ylidene]methyl}-4H-pyrido[1,2-a]pyrimidin-4-one; 4H-Pyrido[1,2-a]pyrimidin-4-one, 2-[2-(2-hydroxyethoxy)ethyl]amino]-3-[[4-oxo-3-(2-phenylethyl)-2-thioxo-5-thiazolidinylidene]methyl]-; 489404-52-6; UNII-9J5K3V8B4T; 9J5K3V8B4T; CHEMBL3183452; DTXSID60635623; SCHEMBL15506297
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure identity, strength, and composition. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements. We support development projects with cGMP-compliant manufacturing capabilities for later-stage projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	Yellow to orange solid powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.