Description

Methyl 2-Chloro-4-(4-Fluorophenyl)-6-Isopropylpyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyrimidine core structure. This compound is of critical importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug molecules, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its heterocyclic structure for biological activity.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex pyrimidine-based scaffolds in medicinal chemistry programs.
• Material Science Research: Investigated for potential use in creating specialty polymers or organic electronic materials due to its aromatic and halogenated structure.

Basic Information

Product Name	Methyl 2-Chloro-4-(4-Fluorophenyl)-6-Isopropylpyrimidine-5-Carboxylate
CAS No.	488798-38-5
Molecular Formula	C15H14ClFN2O2
Molecular Weight	308.73 g/mol
Synonyms	Methyl 2-chloro-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-chloro-4-(4-fluorophenyl)-6-(1-methylethyl)-, methyl ester; 2-Chloro-4-(4-fluorophenyl)-6-isopropylpyrimidine-5-carboxylic acid methyl ester; Methyl 2-chloro-4-(p-fluorophenyl)-6-isopropylpyrimidine-5-carboxylate; CAS 488798-38-5
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Chloro-4-(4-Fluorophenyl)-6-Isopropylpyrimidine-5-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.