Description

Ethyl 6-(3-Acetoxyphenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new chemical entities.
• API Synthesis: Serves as a core scaffold for constructing complex molecules with potential biological activity in pre-clinical and clinical development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of investigational drugs.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study specific enzyme or receptor interactions.

Basic Information

Product Name	Ethyl 6-(3-Acetoxyphenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate
CAS No.	488747-44-0
Molecular Formula	C20H20N2O5S
Molecular Weight	400.45 g/mol
Synonyms	Ethyl 6-(3-acetyloxyphenyl)-8-methyl-4-oxo-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate; 2H,6H-Pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid, 6-(3-acetyloxyphenyl)-3,4-dihydro-8-methyl-4-oxo-, ethyl ester; 488747-44-0; Ethyl 6-(3-acetoxyphenyl)-8-methyl-4-oxo-3,4-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate; SCHEMBL21806227; AKOS040759296; ZINC000003869756; A1-00819
EINECS	Contact for details

Quality Control

Our Ethyl 6-(3-Acetoxyphenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be sensitive to moisture; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.